Saracens centre Brad Barritt will miss England's second Test with South Africa due to an eye injury.
Barritt was forced off during the second half of England's opening defeat and has subsequently had surgery on a lacerated eyeball.
Sarries fly-half Owen Farrell scored four penalties in England's 22-17 defeat.
Meanwhile, Saracens were beaten 22-20 by BGC Asia Pacific Barbarians in Hong Kong.
Jamie George and Nathan Earle scored for the Men in Black but a late penalty sent them to defeat.